Weng Shao-Wen, Liu Jien-Wei, Chen Wei-Jen, Wang Pei-Wen
Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Jpn J Infect Dis. 2005 Apr;58(2):70-2.
Klebsiella pneumoniae is the leading cause of liver abscess in diabetic patients in Taiwan. We report the case of a diabetic patient with a history of four episodes of K. pneumoniae liver abscess within 3 years. The patient later developed Streptococcus bovis bacteremia originating from a colon tumor with complications of endocarditis, osteomyelitis, and silent splenic abscess. Occult colon tumor may have played an important role in our case, with recurrent infection arising from colonizers of the gastrointestinal tract. As our case shows, the possible association between occult colon tumor and K. pneumoniae liver abscess in diabetic patients should be surveyed.
肺炎克雷伯菌是台湾糖尿病患者肝脓肿的主要病因。我们报告了一名糖尿病患者的病例,该患者在3年内曾4次发生肺炎克雷伯菌肝脓肿。该患者后来发生了源自结肠肿瘤的牛链球菌菌血症,并伴有心内膜炎、骨髓炎和隐匿性脾脓肿等并发症。隐匿性结肠肿瘤可能在我们的病例中起了重要作用,胃肠道定植菌引起了反复感染。正如我们的病例所示,应调查糖尿病患者隐匿性结肠肿瘤与肺炎克雷伯菌肝脓肿之间可能存在的关联。