Czeczot Hanna, Skrzycki Michał, Podsiad Małgorzata, Gawryszewska Ewelina, Nyckowski Paweł, Porembska Zofia
Katedra i Zakfad Biochemii Akademii Medycznej w Warszawie.
Pol Merkur Lekarski. 2005 Jan;18(103):58-61.
In the present work we examined selected parameters of antioxidant status in patients with primary colorectal cancer and liver metastasis of colorectal cancer. Total antioxidant status (TAS), activity of superoxide dismutase (SOD) and catalase (CAT) were examined in colorectal primary cancer, liver metastasis of colorectal cancer and in blood serum of patients before and after surgery. It was found that patients have disordered function of the the antioxidant system. This is demonstrated by decreased TAS and changes in the activity of SOD and CAT, both in tumor tissue and blood serum.
在本研究中，我们检测了原发性结直肠癌患者以及结直肠癌肝转移患者抗氧化状态的选定参数。对结直肠癌原发灶、结直肠癌肝转移灶以及患者手术前后血清中的总抗氧化状态（TAS）、超氧化物歧化酶（SOD）和过氧化氢酶（CAT）活性进行了检测。结果发现，患者的抗氧化系统功能紊乱。肿瘤组织和血清中TAS降低以及SOD和CAT活性变化均证实了这一点。
