Bewtra Chhanda, Xie Qing M, Hunter William J, Jurgensen William
Department of Pathology, Creighton University Medical Center, Omaha, Neb 68131, USA.
Arch Pathol Lab Med. 2005 May;129(5):e124-5. doi: 10.5858/2005-129-e124-IUACRA.
Squamous metaplasia of endometrium is mostly manifested by morules or nodules of benign nonkeratinizing squamous cells intimately mixed with benign or malignant endometrial glands. It has been described with low-grade adenocarcinoma of the endometrium, as well as with various benign conditions, including hyperplasia, chronic endometritis, and endometrial polyps. However, extensive plaquelike, keratinizing squamous change is distinctly uncommon. To our knowledge, we describe the first case of extensive benign squamous keratinization with underlying endometrial adenocarcinoma.
子宫内膜鳞状化生主要表现为良性非角化鳞状细胞的桑葚体或结节，与良性或恶性子宫内膜腺体紧密混合。它已被描述与子宫内膜低级别腺癌以及各种良性情况相关，包括增生、慢性子宫内膜炎和子宫内膜息肉。然而，广泛的斑块状、角化性鳞状改变明显不常见。据我们所知，我们描述了首例伴有潜在子宫内膜腺癌的广泛良性鳞状角化病例。
