Elamthuruthy A T, Shah C R, Khan T A, Tatke P A, Gabhe S Y
B/101, Mukund Police Station Road, Dahisar (East), Mumbai 400068, India.
J Pharm Biomed Anal. 2005 Apr 29;37(5):937-41. doi: 10.1016/j.jpba.2004.11.044. Epub 2005 Jan 13.
Kumariasava is a marketed ayurvedic formulation containing Aloe vera as one of the main ingredients. Present study aims to standardize Kumariasava based upon chromatographic and spectral studies. Various extracts of Kumariasava have been prepared and evaluated. Chloroform extract indicated presence of three well-resolved fluorescent components. Spectral data of these three fractions (III-V) have been reported as a valuable analytical tool for routine standardization of Kumariasava. Fraction V indicated presence of anthraquinones, which is reported as the main constituent of aloe, namely aloin. Hence, isolation and evaluation of aloin has been undertaken. Aloin can be used as possible marker compound for standardization of Kumariasava.