一种罕见的女性生殖道肿瘤：外阴良性颗粒细胞瘤：病例报告及文献复习
A rare female genital tract tumor: benign granular cell tumor of vulva: case report and review of the literature.
作者信息
Cheewakriangkrai Chalong, Sharma Sameer, Deeb George, Lele Shashikant
机构信息
Department of Gynecologic Oncology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.
出版信息
Gynecol Oncol. 2005 May;97(2):656-8. doi: 10.1016/j.ygyno.2004.12.058.
BACKGROUND
The granular cell tumor (GCT) of vulva is a rare female genital tract tumor.
CASE
A 59-year-old female was incidentally noted to have a 1-cm sized lump in her left labium majus that subsequently increased in size to approximately 4 cm. The mass was totally excised under general anesthesia. Her postoperative follow-up was uneventful. Histologic examination of the tumor showed sheets and clusters of infiltrating tumor cells with morphologic features consistent with granular cell tumor.
CONCLUSION
Although benign and slow growing, it has a tendency for recurrence and can cause morbidity and mortality when presenting with multicentric or multiple organ involvement due to the lack of effective systemic therapy. Therefore, clinicians and pathologists should be aware of its clinical and histopathologic features.
背景
外阴颗粒细胞瘤（GCT）是一种罕见的女性生殖道肿瘤。
病例
一名59岁女性偶然发现左侧大阴唇有一个1厘米大小的肿块，随后肿块增大至约4厘米。在全身麻醉下将肿块完全切除。术后随访无异常。肿瘤的组织学检查显示有片状和簇状浸润性肿瘤细胞，其形态学特征与颗粒细胞瘤一致。
结论
尽管该肿瘤为良性且生长缓慢，但由于缺乏有效的全身治疗，当出现多中心或多器官受累时，它有复发倾向，并可导致发病和死亡。因此，临床医生和病理学家应了解其临床和组织病理学特征。
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