Sun J, Wang J, Liu J
Occupational Health Institute of Baiyin Nonferrous Metals Cooperation, China.
Biomed Environ Sci. 1992 Mar;5(1):76-85.
A study on the dose-effect relationship between blood lead level and FEP, ZPP, CPU, and ALAU among 250 lead smelter workers was conducted. A nonlinear regression model of a dose-effect relationship between blood lead and porphyrin metabolism indicators was established. The upper limit of normal values of these indicators were estimated from blood lead levels by these nonlinear regression equations. The diagnostic significance was evaluated by multiregression and discriminant analysis. This study would be helpful to the decision-making policy in revising the current diagnostic criteria for occupational lead poisoning.
对250名铅冶炼工人的血铅水平与FEP、ZPP、CPU和ALAU之间的剂量-效应关系进行了研究。建立了血铅与卟啉代谢指标之间剂量-效应关系的非线性回归模型。通过这些非线性回归方程，根据血铅水平估计这些指标的正常上限值。采用多元回归和判别分析对诊断意义进行评估。本研究将有助于修订现行职业性铅中毒诊断标准的决策政策。
