Grzanka Katarzyna, Kucharz Eugeniusz Józef
Kliniki Chorób Wewnetrznych i Reumatologii, Slaskiej Akademii Medycznej w Katowicach.
Wiad Lek. 2004;57(11-12):663-71.
Vitamin D-resistant rickets is a group of rare disease characterized by lack of reaction to vitamin D administered in doses sufficient to manage patients with rickets caused by vitamin D deficiency. These disorders result from disturbed metabolism and activity of vitamin D and/or disturbed phosphate metabolism. The most common vitamin D-resistant form of rickets is X-linked hypophosphatemic vitamin D-resistant rickets. Other forms are as the following: oncogenic hypophosphatemic osteomalacia, autosomal dominant hypophosphatemic rickets, hereditary hypophosphatemic rickets with hypercalciuria and pseudo-vitamin D deficient rickets type I and II.
维生素D抵抗性佝偻病是一组罕见疾病，其特征是对给予足以治疗维生素D缺乏所致佝偻病患者的剂量的维生素D缺乏反应。这些病症是由维生素D的代谢和活性紊乱和/或磷酸盐代谢紊乱引起的。最常见的维生素D抵抗性佝偻病形式是X连锁低磷性维生素D抵抗性佝偻病。其他形式如下：肿瘤性低磷性骨软化症、常染色体显性低磷性佝偻病、伴有高钙尿症的遗传性低磷性佝偻病以及I型和II型假性维生素D缺乏性佝偻病。
