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转移性前列腺癌患者的局部和全身治疗:原发肿瘤是否应接受治疗?

Local and systemic therapy for patients with metastatic prostate cancer: should the primary tumor be treated?

作者信息

Canby-Hagino Edith D, Swanson Gregory P, Crawford E David, Basler Joseph W, Hernandez Javier, Thompson Ian M

机构信息

Department of Urology, University of Texas Health Sciences Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

出版信息

Curr Urol Rep. 2005 May;6(3):183-9. doi: 10.1007/s11934-005-0006-5.

DOI:10.1007/s11934-005-0006-5
PMID:15869722
Abstract

Data from well-designed, prospective clinical trials are lacking to support treatment of primary tumor in men diagnosed with metastatic prostate cancer. However, a growing body of evidence suggests that treatment of the primary tumor may enhance cancer control and survival in some men. This evidence is examined and recommendations are made for identifying patients with metastatic prostate cancer who may benefit from definitive treatment of the prostate tumor.

摘要

缺乏来自设计良好的前瞻性临床试验的数据来支持对诊断为转移性前列腺癌的男性原发性肿瘤进行治疗。然而,越来越多的证据表明,对原发性肿瘤的治疗可能会增强某些男性的癌症控制并提高生存率。本文对这一证据进行了研究,并就如何识别可能从前列腺肿瘤确定性治疗中获益的转移性前列腺癌患者提出了建议。

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引用本文的文献

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Front Oncol. 2020 Dec 8;10:527952. doi: 10.3389/fonc.2020.527952. eCollection 2020.
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Local Treatment of Metastatic Prostate Cancer: What is the Evidence So Far?

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Cancer statistics, 2005.2005年癌症统计数据。
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Current status of local salvage therapies following radiation failure for prostate cancer.前列腺癌放疗失败后局部挽救性治疗的现状
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Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer.多西他赛联合泼尼松或米托蒽醌联合泼尼松用于晚期前列腺癌治疗
N Engl J Med. 2004 Oct 7;351(15):1502-12. doi: 10.1056/NEJMoa040720.
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Is there a "curative" role of radiotherapy for clinically localized hormone refractory prostate cancer?对于临床局限性激素难治性前列腺癌,放射治疗是否具有“治愈”作用?
Am J Clin Oncol. 2004 Jun;27(3):264-8. doi: 10.1097/01.coc.0000092565.46506.bc.
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External beam radiotherapy for clinically node-negative, localized hormone-refractory prostate cancer: impact of pretreatment PSA value on radiotherapeutic outcomes.临床淋巴结阴性、局部激素难治性前列腺癌的体外照射放疗:治疗前前列腺特异抗原值对放疗结果的影响
Int J Radiat Oncol Biol Phys. 2004 Jun 1;59(2):372-9. doi: 10.1016/j.ijrobp.2003.10.033.
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Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much?基于氟尿嘧啶的II期和III期结肠癌辅助治疗的汇总分析:哪些患者受益以及受益程度如何?
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