Cooper A J, Friedberg E C
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235.
Gene. 1992 May 1;114(1):145-8. doi: 10.1016/0378-1119(92)90721-z.
Sequencing of the region upstream from the yeast RAD3 gene has revealed an open reading frame (ORF) of 225 amino acids (aa) that could encode a 25.3-kDa polypeptide. The predicted aa sequence of this ORF is homologous with that of several eukaryotic adenylate kinase (Adk)-encoding genes, including the yeast gene, ADK1. These findings suggest that the yeast Saccharomyces cerevisiae has a second Adk-encoding gene, tentatively designated as ADK2.
对酵母RAD3基因上游区域进行测序,发现了一个225个氨基酸(aa)的开放阅读框(ORF),它可能编码一个25.3 kDa的多肽。该ORF预测的氨基酸序列与几个真核腺苷酸激酶(Adk)编码基因的序列同源,包括酵母基因ADK1。这些发现表明,酿酒酵母有第二个Adk编码基因,暂命名为ADK2。