Mollet Nico R, Cademartiri Filippo, Nieman Koen, Saia Francesco, Lemos Pedro A, McFadden Eugene P, Serruys Patrick W, Krestin Gabriel P, de Feyter Pim J
Department of Cardiology, Thoraxcenter, Rotterdam, The Netherlands.
Am J Cardiol. 2005 May 15;95(10):1165-9. doi: 10.1016/j.amjcard.2005.01.043.
We performed coronary plaque imaging with 16-row multislice computed tomography in 85 patients who had stable angina pectoris and a high pretest likelihood of having coronary plaque to evaluate plaque burden, i.e., extent (number of diseased coronary segments) and size (small vs large) of plaque. We also assessed type of plaque (calcified, noncalcified, or mixed) and its anatomic distribution. Of 85 patients included, 78 (92%) had fully evaluable multislice computed tomograms that allowed assessment of coronary plaque burden, including major and side branches (>or=2 mm), yielding a total of 855 segments. These 78 patients (92% men; mean age +/- SD 58 +/- 11.5 years) were in sinus rhythm, with heart rates of <70 beats/min (spontaneous or induced by beta blocker). Plaque was detected in 57% of all segments (487 of 855). The mean number of segments with plaque per patient +/- SD was 6.2 +/- 3.9. Plaque was classified as large in 33% of segments and small in 67%. Overall, 65% of plaques were calcified, 24% were noncalcified, and 11% were mixed. Plaques were predominantly located in the proximal and middle segments of the main coronary vessels.
我们对85例患有稳定型心绞痛且冠状动脉斑块预测试验可能性高的患者进行了16排多层计算机断层扫描冠状动脉斑块成像，以评估斑块负荷，即斑块的范围（病变冠状动脉节段数）和大小（小斑块与大斑块）。我们还评估了斑块的类型（钙化、非钙化或混合性）及其解剖分布。在纳入的85例患者中，78例（92%）有可完全评估的多层计算机断层扫描图像，可用于评估冠状动脉斑块负荷，包括主要分支和侧支（≥2mm），共计855个节段。这78例患者（92%为男性；平均年龄±标准差58±11.5岁）为窦性心律，心率<70次/分钟（自发或由β受体阻滞剂诱发）。在所有节段中，57%（855个节段中的487个）检测到斑块。每位患者有斑块节段的平均数±标准差为6.2±3.9。33%的节段斑块被分类为大斑块，67%为小斑块。总体而言，65%的斑块为钙化斑块，24%为非钙化斑块，11%为混合性斑块。斑块主要位于冠状动脉主干的近端和中段。
