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根治性会阴前列腺切除术的当代评估

Contemporary appraisal of radical perineal prostatectomy.

作者信息

Janoff Daniel M, Parra Raul O

机构信息

Divisions of Urology, Oregon Health and Sciences University, Portland, Oregon, USA.

出版信息

J Urol. 2005 Jun;173(6):1863-70. doi: 10.1097/01.ju.0000161483.65619.b3.

Abstract

PURPOSE

In the age of minimally invasive surgery there has been renewed interest in the perineal approach for the surgical treatment of prostate cancer. We reviewed recent publications regarding radical perineal prostatectomy (RPP) in an effort to define its role in the current management of localized prostate malignancy. At the same time we reviewed the relevant perineal anatomy and surgical approach necessary to perform this operation.

MATERIALS AND METHODS

We performed a review of the literature with respect to RPP and included our own extensive experience with this operation, emphasizing patient selection, the current role of pelvic lymph node dissection, surgical anatomy, oncological outcomes and complications.

RESULTS

RPP is an effective treatment for localized adenocarcinoma of the prostate with oncological outcomes similar to those of the retropubic technique. In comparison to RRP, patients undergoing RPP have less postoperative discomfort, more rapid return of bowel function, more rapid return to work and a decreased transfusion rate. In addition, RRP is now often performed with cavernous nerve sparing. Prostate specific antigen screening has made the rate of lymph node metastasis low enough to omit lymphadenectomy in many cases.

CONCLUSIONS

There is still a role for RPP in the treatment of localized prostate cancer. Erectile dysfunction after nerve sparing and incontinence rates are similar to those of RRP. In addition, it is less morbid then RRP without being as technically challenging as laparoscopic radical prostatectomy.

摘要

目的

在微创手术时代,人们对经会阴途径治疗前列腺癌重新产生了兴趣。我们回顾了近期有关根治性会阴前列腺切除术(RPP)的文献,以明确其在当前局限性前列腺恶性肿瘤治疗中的作用。同时,我们回顾了实施该手术所需的相关会阴解剖结构和手术方法。

材料与方法

我们对有关RPP的文献进行了综述,并纳入了我们自己在该手术方面的丰富经验,重点关注患者选择、盆腔淋巴结清扫的当前作用、手术解剖、肿瘤学结局和并发症。

结果

RPP是治疗局限性前列腺腺癌的有效方法,其肿瘤学结局与耻骨后技术相似。与耻骨后根治性前列腺切除术(RRP)相比,接受RPP的患者术后不适更少,肠功能恢复更快,恢复工作更快,输血率降低。此外,现在RRP常采用保留海绵体神经的方法。前列腺特异性抗原筛查使淋巴结转移率足够低,以至于在许多情况下可省略淋巴结切除术。

结论

RPP在局限性前列腺癌的治疗中仍有作用。保留神经后的勃起功能障碍和尿失禁发生率与RRP相似。此外,它比RRP的创伤性小,且不像腹腔镜根治性前列腺切除术那样在技术上具有挑战性。

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