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在先天性心脏病中使用支架维持心房缺损和Fontan开窗。

Use of stents to maintain atrial defects and fontan fenestrations in congenital heart disease.

作者信息

Bar-Cohen Yaniv, Perry Stan B, Keane John F, Lock James E

机构信息

Department of Cardiology, Children's Hospital, Boston, Massachusetts 02115, USA.

出版信息

J Interv Cardiol. 2005 Apr;18(2):111-8. doi: 10.1111/j.1540-8183.2005.04049.x.

Abstract

Maintaining patent atrial septal communications or fenestrations can be vital in conditions requiring adequate decompression of the atria or Fontan baffle. We have recently deployed stents for this purpose, and the aim of this retrospective analysis is to describe our experience. All 26 patients undergoing such stent placement were retrospectively studied and for neonates with hypoplastic left heart syndrome (HLHS) and patients with Fontan fenestrations, their data were compared to controls undergoing transseptal static balloon dilation during the same time period. All 7 stented neonates with HLHS survived to their Norwood procedure and 57% survived to hospital discharge, similar to those who had static balloon dilation. Complications occurred in both HLHS groups but transient complete heart block was only seen in the control group, which also had larger balloons used (10.3 mm vs 7 mm, P=0.002). The success rate for patients undergoing stent placement in Fontan fenestrations was 64% compared to 76% with dilation alone. Complications were seen in 64% of the Fontan stented group compared to 39% for controls. There were 5 other patients with complex lesions (3 of whom were on the Extracorporeal Membrane Oxygenator) in whom stent placement successfully maintained atrial communication patency. Atrial septal stent placement in neonates with HLHS with restrictive defects is effective and appears at least as safe as static balloon dilation. On the other hand, initial fenestration stent placement is indicated only after extracardiac Fontan procedures in which the previous fenestration location cannot be found.

摘要

在需要心房充分减压或进行Fontan分流术的情况下,维持房间隔交通开放或造瘘至关重要。我们最近已为此目的部署了支架,本回顾性分析的目的是描述我们的经验。对所有26例行此类支架置入术的患者进行回顾性研究,并将患有左心发育不全综合征(HLHS)的新生儿和Fontan造瘘患者的数据与同期接受经房间隔静态球囊扩张术的对照组进行比较。所有7例行支架置入术的HLHS新生儿均存活至诺伍德手术,57%存活至出院,与接受静态球囊扩张术的新生儿相似。两组HLHS患者均出现并发症,但仅在对照组中观察到短暂性完全性心脏传导阻滞,对照组使用的球囊也更大(10.3 mm对7 mm,P = 0.002)。Fontan造瘘患者接受支架置入术的成功率为64%,而单纯扩张术的成功率为76%。Fontan支架置入组64%出现并发症,而对照组为39%。还有5例患有复杂病变的患者(其中3例使用体外膜肺氧合),支架置入术成功维持了房间隔交通开放。对于患有HLHS且存在限制性缺损的新生儿,房间隔支架置入术是有效的,且至少与静态球囊扩张术一样安全。另一方面,仅在无法找到先前造瘘位置的心脏外Fontan手术后才考虑进行初始造瘘支架置入术。

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