Altucher Kristine, Rasmussen Kathleen M, Barden Elizabeth M, Habicht Jean-Pierre
Tompkins Cortland Community College, Dryden, NY, USA.
J Am Diet Assoc. 2005 May;105(5):709-15. doi: 10.1016/j.jada.2005.02.010.
Nutrition supplementation programs are generally targeted to those members of the population who are thought to be at risk of an undesirable outcome, but not all who participate in such programs respond to them. We sought to identify determinants of improvement in hemoglobin concentration among young children in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC).
We conducted an observational study using data from 9,930 children who were enrolled in the Massachusetts WIC program and had data available on their hemoglobin values at both 1 and 2 years of age. Predictors of change in hemoglobin concentration between these ages were studied using multivariate statistical modeling.
Overall, hemoglobin concentrations increased from age 1 to 2 years in those who had been breastfed 25 or more weeks (P < .0001) and were female (P < .01), and decreased with increasing weight at 1 year of age (P < .001). The determinants of change in hemoglobin concentration differed from the determinants of hemoglobin concentration at age 1 year.
The analytical approach used here could be extended to identify subgroups of WIC participants likely to improve in other outcomes. If current efforts to increase the duration of breastfeeding among WIC participants are successful, the importance of WIC in improving hemoglobin concentration among young children also will increase.
营养补充计划通常针对那些被认为有不良后果风险的人群，但并非所有参与此类计划的人都会对此做出反应。我们试图确定妇女、婴儿和儿童特别补充营养计划（WIC）中幼儿血红蛋白浓度改善的决定因素。
我们进行了一项观察性研究，使用了来自9930名参加马萨诸塞州WIC计划的儿童的数据，这些儿童在1岁和2岁时都有血红蛋白值数据。使用多变量统计模型研究了这些年龄之间血红蛋白浓度变化的预测因素。
总体而言，母乳喂养25周或更长时间的儿童（P < .0001）和女性儿童（P < .01）的血红蛋白浓度从1岁到2岁有所增加，而随着1岁时体重增加而降低（P < .001）。血红蛋白浓度变化的决定因素与1岁时血红蛋白浓度的决定因素不同。
这里使用的分析方法可以扩展到识别WIC参与者中可能在其他结果方面得到改善的亚组。如果目前在WIC参与者中增加母乳喂养持续时间的努力取得成功，WIC在改善幼儿血红蛋白浓度方面的重要性也将增加。
