用彩色双功能超声评估肿瘤氧合：一种新方法。
Evaluation of tumor oxygenation by color duplex sonography: a new approach.
作者信息
Di Martino Ercole F N, Gagel Bernd, Schramm Oliver, Maneschi Payam, Westhofen Martin
机构信息
Departments of Oto-Rhino-Laryngology and Plastic Head and Neck Surgery, Aachen University, Pauwelsstrasse 30, D-52074 Aachen, Germany.
出版信息
Otolaryngol Head Neck Surg. 2005 May;132(5):765-9. doi: 10.1016/j.otohns.2005.01.033.
OBJECTIVE
Description of a new noninvasive method for the evaluation of tissue oxygenation in head and neck cancer.
STUDY DESIGN AND SETTING
Prospective nonrandomized controlled study in an academic medical center on 20 patients with neck metastases of head and neck cancer. Metastases were investigated using color duplex sonography and pO2 histography. The vascularization in sonography was quantitatively evaluated by color pixel density and compared to the pO2 values of the same nodes.
RESULTS
The correlation between vascularization and flow velocity was 0.71. For the mean/median pO2 -values and for the pO2 readings <10.0 mmHg correlations were r = 0.65 / 0.76 and 0.71.
CONCLUSION
This sonographic method allows a safe and reliable evaluation of oxygenation in metastases of head and neck cancer.
SIGNIFICANCE
The new approach is an alternative to pO2 histography and may play a future role in the planning of radiotherapy in the neck.
目的
描述一种用于评估头颈癌组织氧合的新型非侵入性方法。
研究设计与背景
在一所学术性医疗中心对20名头颈癌颈部转移患者进行前瞻性非随机对照研究。使用彩色双功超声和pO2组织成像技术对转移灶进行研究。通过彩色像素密度对超声检查中的血管化进行定量评估，并与相同淋巴结的pO2值进行比较。
结果
血管化与血流速度之间的相关性为0.71。对于平均/中位数pO2值以及pO2读数<10.0 mmHg的情况，相关性分别为r = 0.65 / 0.76和0.71。
结论
这种超声检查方法能够对头颈癌转移灶的氧合情况进行安全可靠的评估。
意义
这种新方法是pO2组织成像技术的一种替代方法，可能在颈部放射治疗计划中发挥未来作用。
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