Buckberg Gerald
David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1741, USA.
Heart Fail Rev. 2004 Oct;9(4):255-68; discussion 347-51. doi: 10.1007/s10741-005-6803-6.
The Reviews report will establish guidelines that underlie why the "restoration concept" may develop a paradigm shift in thinking, by addressing the geometric underpinnings of heart failure and their evolution. This presentation will (a) show that the underlying structure of the failing dilated heart involves a cardiac architectural change from the normal elliptical shape toward a dilated spherical form, (b) define the anatomic framework of this shape change, (c) convey the functional characteristics of heart function that result from this architectural underpinning, (d) describe the pattern of CHF development, (e) indicate imaging measurement guidelines to follow as heart form adversely changes from ellipse to sphere, (f) identify how such architectural changes alter prognosis, and (g) develop a historical evolution of surgical approaches to alter form to improve function to create the background for subsequent RESTORE team reports of current restoration to treat CHF and its complications.
《综述报告》将通过探讨心力衰竭的几何基础及其演变,确立“恢复概念”可能引发思维范式转变的指导原则。本报告将:(a)表明衰竭扩张型心脏的潜在结构涉及从正常椭圆形向扩张球形的心脏结构变化;(b)定义这种形状变化的解剖学框架;(c)阐述这种结构基础所导致的心脏功能的功能特征;(d)描述心力衰竭的发展模式;(e)指出随着心脏形状从椭圆形向球形不利变化时应遵循的成像测量指导原则;(f)确定这种结构变化如何改变预后;(g)梳理通过改变形状来改善功能的手术方法的历史演变,为后续RESTORE团队关于当前治疗心力衰竭及其并发症的恢复治疗的报告奠定基础。