Linkage mapping of the [Pro2]somatostatin-14 gene in zebrafish: evolutionary perspectives.

作者信息

Tostivint Hervé, Joly Lucille, Lihrmann Isabelle, Conlon J Michael, Ekker Marc, Vaudry Hubert

机构信息

European Institute for Peptide Research (IFRMP 23), Laboratory of Cellular and Molecular Neuroendocrinology, INSERM U-413, University of Rouen, Mont-Saint-Aignan, France.

出版信息

Ann N Y Acad Sci. 2005 Apr;1040:486-9. doi: 10.1196/annals.1327.098.

DOI:10.1196/annals.1327.098

PMID:15891097

Abstract

Radiation hybrid mapping assigned the zebrafish [Pro(2)]somatostatin-14 (also termed somatostatin 2; SS2) gene to linkage group 23 of the zebrafish genome, close to the marker nadl1.2. Comparative genomic analysis revealed conserved syntenies of the SS2 gene locus with part of the human 1p36 region, where the cortistatin gene is located. This observation strongly suggests that the SS2 gene in nonmammalian species and the cortistatin gene in mammals are orthologous.

摘要