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颅内脂肪瘤——一项临床研究。

Intracranial lipomas--a clinical study.

作者信息

Yilmaz Nebi, Unal Ozkan, Kiymaz Nejmi, Yilmaz Cahide, Etlik Omer

机构信息

Department of Neurosurgery, School of Medicine, Yuzuncu Yil Universitesi Tip Fakultesi Arastirma Hastanesi Nöroşirürji Kliniği, 65200 Van, Turkey.

出版信息

Clin Neurol Neurosurg. 2006 Jun;108(4):363-8. doi: 10.1016/j.clineuro.2005.04.003.

Abstract

OBJECTIVE

This study aimed to investigate the localization of the lipoma, as well as associated intracranial and extracranial lesions in 14 patients immediately following hospital admission. The pathological findings from the neurological examinations of these patients are also investigated.

METHODS

Fourteen patients who were admitted to our clinic with a variety of symptoms and diagnosed with intracranial lipoma were included in the study. Problems presented upon admission, neurological findings, and other existing system abnormalities were evaluated. Localization of the lipomas and accompanying pathologies were determined by using computerised tomography and magnetic resonance imaging.

RESULTS

The most frequent reasons for admission of patients with intracranial lipomas were: headache 7 (50%), trauma 3 (21.5%), epilepsy 3 (21.5%) and one with symptoms due to the local mass effect of tumor (7%). Although the pericallosal region is accepted as the region where lipomas commonly occur, this study found the most frequent occurrence in the quadrigeminal cistern. Intracranial lipoma calcification was only evident in 1 of the 14 patients. In addition, contrary to the expectations, intracranial and extracranial lesions accompanying lipomas were rare. All patients received systematic treatment.

CONCLUSION

This study showed that intracranial lipomas are more frequent in the quadrigeminal region of the brain; most are asymptomatic, generally caught incidentally; and accompanying intracranial and extracranial pathologies are less common than expected.

摘要

目的

本研究旨在调查14例患者入院后即刻颅内脂肪瘤的定位以及相关的颅内和颅外病变。同时也对这些患者神经学检查的病理结果进行研究。

方法

本研究纳入了14例因各种症状入院并被诊断为颅内脂肪瘤的患者。对入院时出现的问题、神经学检查结果以及其他现有的系统异常情况进行了评估。通过计算机断层扫描和磁共振成像确定脂肪瘤的定位及伴随的病变情况。

结果

颅内脂肪瘤患者入院的最常见原因是:头痛7例(50%)、外伤3例(21.5%)、癫痫3例(21.5%)以及1例因肿瘤局部占位效应出现症状(7%)。虽然胼胝体周围区域被认为是脂肪瘤常见的发生部位,但本研究发现最常发生于四叠体池。14例患者中仅1例颅内脂肪瘤有钙化表现。此外,与预期相反,脂肪瘤伴随的颅内和颅外病变很少见。所有患者均接受了系统治疗。

结论

本研究表明颅内脂肪瘤在脑的四叠体区域更为常见;大多数无症状,通常为偶然发现;且伴随的颅内和颅外病变比预期少见。

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