使用TMS-1测量圆锥角膜时角膜地形图测量的可重复性。
Repeatability of corneal topography measurement in keratoconus with the TMS-1.
作者信息
McMahon Timothy T, Anderson Robert J, Roberts Cynthia, Mahmoud Ashraf M, Szczotka-Flynn Loretta B, Raasch Thomas W, Friedman Nina E, Davis Larry J
机构信息
Department of Ophthalmology & Visual Sciences, University of Illinois College of Medicine at Chicago, Chicago, Illinois (TTM), the Division of Epidemiology & Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois (RJA), the Department of Ophthalmology, The Ohio State University, Columbus, Ohio (CR, AMM), the Department of Ophthalmology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio (LBSF), the Ohio State University, College of Optometry, Columbus, Ohio (TWR), the School of Optometry, University of California, Berkeley, California (NEF), and the College of Optometry, University of Missouri-St. Louis, St. Louis. Missouri (LJD).
出版信息
Optom Vis Sci. 2005 May;82(5):405-415. doi: 10.1097/01.OPX.0000162667.22303.76.
PURPOSE
The purpose of this study was to report the test-retest variability of simulated indices derived from the TMS-1 topography instrument (Tomey Technology, Waltham, MA) in keratoconus subjects enrolled in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study.
METHODS
Four images were taken at an initial visit and at a repeat visit several weeks later. From these images, 17 indices were simulated from published formulas. Mixed-model analysis was used on test-retest data from the TMS-1 videokeratography instrument during the baseline year. This analysis yields estimates of within- and between-visit variability.
RESULTS
Repeatability analysis revealed that within-visit standard errors were 1.0 to 5.9 times greater in keratoconus eyes than in normal controls when two images were analyzed from each visit. These values changed only slightly when more images were used. The ratio of between-visit standard errors of the indices were nearly equally greater than normal controls for (0.9-4.6 and 0.9-4.3) two images per eye and all images per eye, respectively.
CONCLUSIONS
These results suggest that the repeatability of simulated indices derived from TMS-1 topography in keratoconus subjects is poorer than in normal controls.
目的
本研究旨在报告在圆锥角膜协作纵向评估（CLEK）研究中，圆锥角膜患者使用TMS - 1地形图仪（拓美科技公司，马萨诸塞州沃尔瑟姆）得出的模拟指标的重测变异性。
方法
在初次就诊时及几周后的复诊时拍摄四张图像。从这些图像中，根据已发表的公式模拟出17项指标。对基线年份TMS - 1角膜地形图仪的重测数据进行混合模型分析。该分析得出就诊内和就诊间变异性的估计值。
结果
重复性分析显示，当每次就诊分析两张图像时，圆锥角膜眼的就诊内标准误差比正常对照组大1.0至5.9倍。当使用更多图像时，这些值变化不大。对于每只眼睛两张图像和每只眼睛所有图像的情况，指标的就诊间标准误差比分别比正常对照组大近相同倍数（0.9 - 4.6和0.9 - 4.3）。
结论
这些结果表明，圆锥角膜患者中由TMS - 1地形图得出的模拟指标的重复性比正常对照组差。
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