Department of Optometry, Faculty of Rehabilitation, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Damavand Street, Tehran, Iran.
Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Int Ophthalmol. 2023 Aug;43(8):2897-2915. doi: 10.1007/s10792-023-02693-3. Epub 2023 Apr 15.
To determine the keratometry measurement agreement using Sirius corneal topography and Scheimpflug camera, Tomey corneal topography, Topcon autokeratorefractometer, and Tomey OA-2000 optical biometry in eyes with different severity of keratoconus.
In this retrospective study 115 eyes in different stages of keratoconus were divided into 2 groups of mild (stage 1), and moderate to severe keratoconus (stages 2, 3), according to the Amsler-Krumeich classification. Keratometry measurements were obtained using Sirius corneal topography and Scheimpflug camera (phoenix V3.7.01.08), Tomey corneal topography (Tms SW22C-200S-200), Topcon autokeratorefractometer (KR8900), and Tomey optical biometry (OA-2000 Opt-Meas V.4E).
In group 1 All devices demonstrated fair agreement in average keratometry values (95% LoA range > 1 D). However, it was poorer for group 2 (95% LOA range > 3 D). In group 1 Bonferroni test revealed statistically significant difference in average K readings among (Topcon autokeratorefractometer 8900 and Tomey OA-2000 biometry, p < 0.01), and between (Tomey topography and Topcon autokeratorefractometer, p < 0.05). Also in group 2 significant difference was observed in the average keratometry of the most instruments (p < 0.01) except for the (Tomey topography and Topcon autokeratorefractometer) and (Tomey topography and Tomey OA-2000 biometry.
According to our investigation in mild, moderate and severe keratoconus the agreement in K reading between Topcon autokeratorefractometer, OA-2000 optical biometry, Sirius topography and Tomey topography was poor. The agreement declines especially in the steep meridian and it was not acceptable clinically. These devices should not be applied interchangeably.
使用 Sirius 角膜地形仪和 Scheimpflug 相机、Tomey 角膜地形仪、Topcon 自动角膜曲率计和 Tomey OA-2000 光学生物测量仪,确定不同程度圆锥角膜的角膜曲率测量一致性。
在这项回顾性研究中,根据 Amsler-Krumeich 分类,将 115 只不同阶段的圆锥角膜眼分为轻度(第 1 期)和中重度圆锥角膜(第 2、3 期)两组。使用 Sirius 角膜地形仪和 Scheimpflug 相机(phoenix V3.7.01.08)、Tomey 角膜地形仪(Tms SW22C-200S-200)、Topcon 自动角膜曲率计(KR8900)和 Tomey 光学生物测量仪(OA-2000 Opt-Meas V.4E)获取角膜曲率测量值。
在第 1 组中,所有设备的平均角膜曲率值(95%LoA 范围>1 D)均显示出良好的一致性。然而,对于第 2 组(95%LOA 范围>3 D),情况则较差。在第 1 组中,Bonferroni 检验显示,Topcon 自动角膜曲率计 8900 和 Tomey OA-2000 生物测量仪之间(p<0.01)以及 Tomey 地形仪和 Topcon 自动角膜曲率计之间(p<0.05)的平均 K 读数存在统计学显著差异。在第 2 组中,除了 Tomey 地形仪和 Topcon 自动角膜曲率计以及 Tomey 地形仪和 Tomey OA-2000 生物测量仪之外,其他大多数仪器的平均角膜曲率都存在显著差异(p<0.01)。
根据我们对轻度、中度和重度圆锥角膜的研究,Topcon 自动角膜曲率计、OA-2000 光学生物测量仪、Sirius 地形仪和 Tomey 地形仪之间的 K 读数一致性较差。这种一致性在陡峭子午线处下降尤其明显,在临床上是不可接受的。这些设备不应该互换使用。