Ishizawa Takeaki, Yamamoto Tetsuhisa, Nishida Koichiro, Tsukui Hajime, Sekikawa Takayoshi
First Department of Surgery, Tokyo Teishin Hospital, 2-14-23 Fujimi, Chiyoda-ku, Tokyo, 102-8798, Japan.
World J Surg. 2005 Jun;29(6):719-22. doi: 10.1007/s00268-005-7888-8.
Some studies have shown reduced portal blood flow in patients with occult hepatic metastases, which may lead to decreased liver volume. A retrospective study was conducted in patients undergoing curative resection for colorectal (n = 63) or gastric (n = 52) cancer. The ratio of the preoperative computed tomography (CT)-estimated liver volume to the standard liver volume (CV/SV ratio) was calculated. The mean +/- SD CT-estimated liver volume was 858 +/-109 in 14 patients who subsequently developed hepatic metastases and 1173 +/- 230 ml in 101 patients without metastases (p < 0.0001). The CV/SV ratio was smaller in patients with metachronous hepatic metastases than in those without (0.78 +/- 0.08 vs. 1.02 + 0.13; p < 0.0001). The results suggest that the liver with occult metastases decreases in size before metastases develop that are detectable using conventional imaging techniques. The CV/SV ratio may be of value in detecting occult hepatic metastases from colorectal and gastric cancer.
一些研究表明，隐匿性肝转移患者的门静脉血流减少，这可能导致肝脏体积减小。对接受结直肠癌（n = 63）或胃癌（n = 52）根治性切除的患者进行了一项回顾性研究。计算术前计算机断层扫描（CT）估计的肝脏体积与标准肝脏体积的比值（CV/SV比值）。14例随后发生肝转移的患者，CT估计肝脏体积的平均值±标准差为858±109，101例未发生转移的患者为1173±230 ml（p < 0.0001）。异时性肝转移患者的CV/SV比值低于无转移患者（0.78±0.08 vs. 1.02 + 0.13；p < 0.0001）。结果表明，在使用传统成像技术可检测到转移灶之前，隐匿性转移的肝脏体积就已减小。CV/SV比值可能对检测结直肠癌和胃癌的隐匿性肝转移有价值。
