Laborde J C, Borenstein N, Behr L, Farah B, Fajadet J
Unité de Cardiologie Interventionnelle, Clinique Pasteur, Toulouse, France.
Catheter Cardiovasc Interv. 2005 Jun;65(2):171-4; discussion 175. doi: 10.1002/ccd.20277.
Recently, percutaneous aortic valve implantation has become an alternative technique to surgical valve replacement in patient at high risk for surgery. Our animal experimentation evaluated the technical feasibility of aortic valve replacement using a bovine pericardium valve sutured on a self-expandable stent in a sheep model. Precise implantation with satisfactory attachment on the adjacent tissues and absence of migration was obtain in 8 out of 14 animals. This study confirmed the feasibility of the endovascular implantation of a pericardium valve sutured on a self-expandable stent in a sheep model.
最近,经皮主动脉瓣植入术已成为手术风险高的患者进行外科瓣膜置换的替代技术。我们的动物实验评估了在绵羊模型中使用缝合在自膨胀支架上的牛心包瓣膜进行主动脉瓣置换的技术可行性。14只动物中有8只实现了精确植入,瓣膜与相邻组织附着良好且无移位。本研究证实了在绵羊模型中经血管植入缝合在自膨胀支架上的心包瓣膜的可行性。