Xu Bo, Wang Bao-jie
School of Forensic Medicine, China Medical University, Shenyang.
Fa Yi Xue Za Zhi. 2005 Feb;21(1):55-7, 60.
The polymorphism of vitamin D receptor (VDR) gene may be associated with bone density, osteoporosis and body height. In this review, the authors summarize the association of the four VDR single nucleotide polymorphisms (SNPs) loci FokI, BsmI, ApaI, TaqI with bone density, osteoporosis and body height reported at home and abroad in recent years. And find that though each country's report may be different, its valuable in the field of genetics, clinical endocrinology and metabolism, especially in the research area of body height in forensic medicine.
维生素D受体（VDR）基因的多态性可能与骨密度、骨质疏松症及身高有关。在这篇综述中，作者总结了近年来国内外报道的VDR四个单核苷酸多态性（SNP）位点FokI、BsmI、ApaI、TaqI与骨密度、骨质疏松症及身高的相关性。并发现尽管各国的报道可能存在差异，但在遗传学、临床内分泌学和代谢领域，尤其是法医学身高研究领域具有重要价值。
