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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Kuribara H, Tadokoro S

Division for Behavior Analysis, Gunma University School of Medicine, Maebashi, Japan.

Prog Neuropsychopharmacol Biol Psychiatry. 1992 May;16(3):389-96. doi: 10.1016/0278-5846(92)90090-2.

The step-through passive avoidance response and discrete lever-press avoidance response of Mongolian gerbils were evaluated to point out the basic problems in the learning and memory tests in this species. 2. Mongolian gerbils exhibited extremely poor acquisition and maintenance of the passive avoidance response. 3. In contrast to the result under the passive avoidance situation, Mongolian gerbils demonstrated an excellent performance under the discrete lever-press avoidance situation. 4. A 5-min brain ischemia elicited a severe morphological damage of the pyramidal cells in hippocampal CA1 region. 5. A small part of such ischemic animals showed a deficit of acquisition of the discrete lever-press avoidance. 6. These results suggest that there is merit and demerit of the acquisition dependent on the type of tasks, and that the brain function of Mongolian gerbils may be maintained even after the ischemic operation.

对长爪沙鼠的穿梭箱被动回避反应和离散杠杆按压回避反应进行评估，以指出该物种学习和记忆测试中的基本问题。2. 长爪沙鼠在被动回避反应的获得和维持方面表现极差。3. 与被动回避情况下的结果相反，长爪沙鼠在离散杠杆按压回避情况下表现出色。4. 5分钟的脑缺血引发了海马CA1区锥体细胞的严重形态损伤。5. 一小部分此类缺血动物在离散杠杆按压回避的获得方面存在缺陷。6. 这些结果表明，学习的优劣取决于任务类型，并且即使在缺血手术后，长爪沙鼠的脑功能仍可能得以维持。

Kuribara H, Tadokoro S

Division for Behavior Analysis, Gunma University School of Medicine, Maebashi, Japan.

Prog Neuropsychopharmacol Biol Psychiatry. 1992 May;16(3):389-96. doi: 10.1016/0278-5846(92)90090-2.

The step-through passive avoidance response and discrete lever-press avoidance response of Mongolian gerbils were evaluated to point out the basic problems in the learning and memory tests in this species. 2. Mongolian gerbils exhibited extremely poor acquisition and maintenance of the passive avoidance response. 3. In contrast to the result under the passive avoidance situation, Mongolian gerbils demonstrated an excellent performance under the discrete lever-press avoidance situation. 4. A 5-min brain ischemia elicited a severe morphological damage of the pyramidal cells in hippocampal CA1 region. 5. A small part of such ischemic animals showed a deficit of acquisition of the discrete lever-press avoidance. 6. These results suggest that there is merit and demerit of the acquisition dependent on the type of tasks, and that the brain function of Mongolian gerbils may be maintained even after the ischemic operation.

对长爪沙鼠的穿梭箱被动回避反应和离散杠杆按压回避反应进行评估，以指出该物种学习和记忆测试中的基本问题。2. 长爪沙鼠在被动回避反应的获得和维持方面表现极差。3. 与被动回避情况下的结果相反，长爪沙鼠在离散杠杆按压回避情况下表现出色。4. 5分钟的脑缺血引发了海马CA1区锥体细胞的严重形态损伤。5. 一小部分此类缺血动物在离散杠杆按压回避的获得方面存在缺陷。6. 这些结果表明，学习的优劣取决于任务类型，并且即使在缺血手术后，长爪沙鼠的脑功能仍可能得以维持。