Lauterbach Stephen R, Torres Gustavo A, Andros George, Oblath Robert W
Section of Vascular Surgery, St Joseph's Medical Center, Burbank, Calif, USA.
Arch Surg. 2005 May;140(5):487-93; discussion 493-4. doi: 10.1001/archsurg.140.5.487.
Infragenicular polytetrafluoroethylene (PTFE)-venous cuff bypass grafting provides acceptable graft patency and limb salvage rates for limb salvage.
Retrospective clinical review of a consecutive series.
Vascular surgical practice during the interval October 1, 2000, to September 1, 2004.
Fifty-one male and 49 female patients whose mean age was 76.9 years were operated on for tissue loss (67%), chronic rest pain (28%), and severe claudication (6%). Fifty-two percent of patients were diabetic and 49% had undergone previous leg bypass surgery. All patients had absent or inadequate greater saphenous vein, and 84 patients had absent or inadequate arm vein.
One hundred five infragenicular PTFE bypasses were performed in these 100 patients. Distal targets were the infragenicular popliteal (40), posterior tibial (35), anterior tibial (16), and peroneal arteries (14). Sixty-eight venous cuffs were constructed from lesser saphenous vein.
Graft patency, limb salvage, and patient survival were analyzed.
Twelve early graft failures resulted in 7 leg amputations. The mean +/- SE 3-year primary patency and limb salvage rates were 64.4% +/- 12.8% and 74.4% +/- 11.9%, respectively. Perioperative mortality was 2.9% and 3-year survival was 38%. Graft follow-up ranged from 1 to 47 months with a mean of 13 months using life-table methods.
For patients requiring arterial revascularization for limb salvage, in which autologous venous conduit is unavailable, distal venous cuff-PTFE bypass provides acceptable patency and limb salvage rates when viewed in the context of short life expectancy for these elderly patients.
膝下聚四氟乙烯(PTFE)-静脉袖套搭桥移植术能为肢体挽救提供可接受的移植血管通畅率和肢体挽救率。
对连续病例系列进行回顾性临床研究。
2000年10月1日至2004年9月1日期间的血管外科实践。
51名男性和49名女性患者,平均年龄76.9岁,因组织缺损(67%)、慢性静息痛(28%)和严重间歇性跛行(6%)接受手术。52%的患者患有糖尿病,49%的患者既往曾接受过腿部搭桥手术。所有患者的大隐静脉均缺失或不适用,84例患者的手臂静脉也缺失或不适用。
对这100例患者进行了105次膝下PTFE搭桥手术。远端目标血管为膝下腘动脉(40例)、胫后动脉(35例)、胫前动脉(16例)和腓动脉(14例)。68个静脉袖套由小隐静脉构建。
分析移植血管通畅率、肢体挽救情况和患者生存率。
12例早期移植血管失败导致7例截肢。平均±标准误的3年一期通畅率和肢体挽救率分别为64.4%±12.8%和74.4%±11.9%。围手术期死亡率为2.9%,3年生存率为38%。采用寿命表法,移植血管随访时间为1至47个月,平均13个月。
对于因肢体挽救需要进行动脉血运重建且无法使用自体静脉管道的患者,考虑到这些老年患者预期寿命较短,远端静脉袖套-PTFE搭桥术可提供可接受的通畅率和肢体挽救率。