Suppr超能文献

基层医疗中的心血管危险因素:方法与基线患病率——DETECT项目

Cardiovascular risk factors in primary care: methods and baseline prevalence rates--the DETECT program.

作者信息

Wittchen H-U, Glaesmer H, März W, Stalla G, Lehnert H, Zeiher A M, Silber S, Koch U, Böhler S, Pittrow D, Ruf G

机构信息

Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany.

出版信息

Curr Med Res Opin. 2005 Apr;21(4):619-30. doi: 10.1185/030079905X38187.

Abstract

OBJECTIVES

DETECT is an epidemiological study in primary care to examine (a) the prevalence rates and comorbidity of diabetes mellitus, hypertension, hyperlipidaemia and coronary heart disease (CHD), and associated conditions; (b) the frequency of behavioural and clinical risk factors for onset and progression; (c) the 12-month course and outcome; and (d) the met and unmet needs for these patients.

METHODS

Three-stage, cross-sectional clinical-epidemiological study with a prospective-longitudinal component in a nationally representative sample of N = 3795 primary care settings [response rate (RR): 60.2%] and N = 55518 patients (RR: 95.5%). Patients completed a standardized assessment, including questionnaires for patients and the physician and diagnostic screening measures (i.e. blood pressure, heart rate, body mass index and waist circumference assessments). A subsample of patients (N = 7519) also completed a standardized laboratory screening program and was followed-up after 12 months. Data were weighted to adjust for non-response, regional distribution and attrition.

RESULTS

(1) Doctors and patients sample can be regarded as representative for primary care settings in Germany. (2) The clinician-rated point prevalence of hypertension is highest (35.5%), followed by hyperlipidaemia (29.1%), diabetes (14.1%) and CHD (12.1%); prevalence rates of each disorder as well as their co-incidence rates increase markedly with age. (3) The vast majority (78%) of all patients revealed multiple (3+) behavioural and clinical risk factors.

CONCLUSION

The findings of DETECT underline the considerable burden for primary care doctors in managing a highly morbid patient population, with predominantly complex risk factor constellations, in routine care. Our data provide, in unprecedented detail, a basis for calculating age-, gender- and risk-group-adjusted risk-factor profiles in routine care.

摘要

目的

DETECT是一项在初级保健机构开展的流行病学研究,旨在调查:(a)糖尿病、高血压、高脂血症和冠心病(CHD)的患病率及合并症,以及相关情况;(b)行为和临床危险因素引发疾病及疾病进展的频率;(c)12个月的病程及转归;(d)这些患者已满足和未满足的需求。

方法

采用三阶段横断面临床流行病学研究,并包含前瞻性纵向研究部分,样本来自全国范围内具有代表性的N = 3795个初级保健机构[应答率(RR):60.2%]以及N = 55518名患者(RR:95.5%)。患者完成了标准化评估,包括患者问卷、医生问卷以及诊断筛查措施(即血压、心率、体重指数和腰围评估)。部分患者子样本(N = 7519)还完成了标准化实验室筛查项目,并在12个月后进行随访。对数据进行加权处理,以校正无应答、地区分布和失访情况。

结果

(1)医生和患者样本可被视为德国初级保健机构的代表性样本。(2)临床医生评定的高血压点患病率最高(35.5%),其次是高脂血症(29.1%)、糖尿病(14.1%)和冠心病(12.1%);每种疾病的患病率及其合并率均随年龄显著增加。(3)所有患者中的绝大多数(78%)存在多种(3种及以上)行为和临床危险因素。

结论

DETECT的研究结果突显了在日常医疗中,初级保健医生管理患有多种疾病、主要是危险因素组合复杂的患者群体时所面临的巨大负担。我们的数据以前所未有的详细程度,为计算日常医疗中年龄、性别和风险组调整后的危险因素概况提供了依据。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验