Tsue Hirohito, Ishibashi Koichi, Takahashi Hiroki, Tamura Rui
Graduate School of Global Environmental Studies, Kyoto University, Kyoto 606-8501, Japan.
Org Lett. 2005 May 26;7(11):2165-8. doi: 10.1021/ol050493i.
[structure: see text]. Described are the preparation, conformation, and crystal structure of exhaustively methylated azacalix[4]arene involving nitrogen atoms as bridging units. NMR and X-ray crystallographic analysis have demonstrated that this novel azacalix[4]arene adopts a 1,3-alternate conformation both in solution and in the solid state. The crystal structure has been characterized solely by intermolecular CH/pi interactions, by which the azacalix[4]arenes mutually interact with each other outside the cavity to furnish a two-dimensional network structure.
[结构：见正文]。描述了以氮原子作为桥连单元的全甲基化氮杂杯[4]芳烃的制备、构象和晶体结构。核磁共振（NMR）和X射线晶体学分析表明，这种新型氮杂杯[4]芳烃在溶液和固态中均采用1,3-交替构象。晶体结构仅通过分子间的CH/π相互作用来表征，通过这种相互作用，氮杂杯[4]芳烃在空腔外部相互作用，形成二维网络结构。
