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[金属结合蛋白的基因及其在重金属生物修复中的应用]

[Genes of metal-binding proteins and their application in bioremediation of heavy metals].

作者信息

Jiao Fang-chan, Mao Xue, Li Run-zhi

机构信息

Center for Agricultural Biotechnology, Shanxi Agricultural University, Taigu, 030801, China.

出版信息

Yi Chuan. 2002 Jan;24(1):82-6.

Abstract

Heavy metal pollution has become a global environmental hazard. The use of microorganisms and plants for the decontamination of heavy metals is recognized as a low lost and high efficiency method for cleaning up metal contamination. It shows that various metal-binding proteins such as metallothioneins (MTs) or phytochelatines (PCs) play an important role in defense systems and detoxification to heavy metals in organisms. Many genes of MTs and PCs have been cloned and utilized successfully in genetically modified bacteria and plants for increasing remediation capacity. These transgenic organisms have been displayed a great potential in bioremediation and phytoremediation of heavy metals.

摘要

重金属污染已成为全球性的环境危害。利用微生物和植物对重金属进行净化被认为是一种低成本、高效率的清除金属污染的方法。这表明各种金属结合蛋白,如金属硫蛋白(MTs)或植物螯合肽(PCs),在生物体对重金属的防御系统和解毒过程中发挥着重要作用。许多MTs和PCs基因已被成功克隆,并应用于转基因细菌和植物中,以提高修复能力。这些转基因生物在重金属的生物修复和植物修复方面显示出巨大潜力。

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