群体感应负向调控铜绿假单胞菌PAO1中III型分泌调节子的表达。
Quorum sensing negatively controls type III secretion regulon expression in Pseudomonas aeruginosa PAO1.
作者信息
Bleves Sophie, Soscia Chantal, Nogueira-Orlandi Patricia, Lazdunski Andrée, Filloux Alain
机构信息
Laboratoire d'Ingénierie des Systèmes Macromoléculaires, CNRS-IBSM-UPR9027, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France.
出版信息
J Bacteriol. 2005 Jun;187(11):3898-902. doi: 10.1128/JB.187.11.3898-3902.2005.
Abstract
A systematic analysis of the type III secretion (T3S) genes of Pseudomonas aeruginosa strain PAO1 revealed that they are under quorum-sensing control. This observation was supported by the down-regulation of the T3S regulon in the presence of RhlR-C4HSL and the corresponding advanced secretion of ExoS in a rhlI mutant.
摘要
对铜绿假单胞菌PAO1菌株的III型分泌（T3S）基因进行的系统分析表明，这些基因受群体感应控制。在存在RhlR-C4HSL的情况下T3S调节子的下调以及rhlI突变体中ExoS相应的提前分泌支持了这一观察结果。
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