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Lack of significant effect of grapefruit juice on the pharmacokinetics of lansoprazole and its metabolites in subjects with different CYP2C19 genotypes.

作者信息

Uno Tsukasa, Yasui-Furukori Norio, Takahata Takenori, Sugawara Kazunobu, Tateishi Tomonori

机构信息

Department of Pharmacy, Hirosaki University Hospital, Hirosaki, Japan.

出版信息

J Clin Pharmacol. 2005 Jun;45(6):690-4. doi: 10.1177/0091270005275430.

DOI:10.1177/0091270005275430
PMID:15901751
Abstract
摘要

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Lack of significant effect of grapefruit juice on the pharmacokinetics of lansoprazole and its metabolites in subjects with different CYP2C19 genotypes.在不同CYP2C19基因型受试者中，葡萄柚汁对兰索拉唑及其代谢产物的药代动力学无显著影响。
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