Dupuytren's disease.

Dupuytren's disease is a nonmalignant fibroproliferative disease that causes progressive and permanent contracture of the palmar fascia with subsequent flexion contracture of the digits. Although the exact etiopathology in the development of Dupuytren's disease is unknown, certain familial, racial, and physiologic factors have been determined. The latest prospective pathogenesis of Dupuytren's disease are presented.