Khoury-Collado Fady, Wehbeh Ammar N, Fisher Allan J, Bombard Allan T, Weiner Zeev
Department of Obstetrics and Gynecology, Lutheran Medical Center, Brooklyn, NY, USA.
Am J Obstet Gynecol. 2005 May;192(5):1469-71. doi: 10.1016/j.ajog.2004.12.037.
We report 2 cases of 47,XXX that were diagnosed prenatally and were screened positive for trisomy 21 by biochemical and ultrasound markers. These cases underline the importance of discussing the sex chromosome abnormalities during the genetic counseling after an abnormal triple screen test or ultrasound examination.
我们报告了2例47,XXX病例，这2例在产前被诊断出来，并且通过生化和超声标志物筛查出21三体呈阳性。这些病例强调了在三联筛查试验或超声检查异常后进行遗传咨询时讨论性染色体异常的重要性。
