De Monte Veronica Eileen, Geffen Gina Malke, May Christopher Randall, McFarland Ken, Heath Philip, Neralic Mendy
Cognitive Psychophysiology Laboratory, University of Queensland, Herston, Brisbane, Queensland, Australia.
J Clin Exp Neuropsychol. 2005 Feb;27(2):224-39. doi: 10.1080/13803390490515766.
This study aimed to investigate the acute effects of mild Traumatic Brain Injury (mTBI) on the performance of a finger tapping and word repetition dual task in order to determine working memory impairment in mTBI. Sixty-four (50 male, 14 female) right-handed cases of mTBI and 26 (18 male and 8 female) right-handed cases of orthopaedic injuries were tested within 24 hours of injury. Patients with mTBI completed fewer correct taps in 10 seconds than patients with orthopaedic injuries, and female mTBI cases repeated fewer words. The size of the dual task decrement did not vary between groups. When added to a test battery including the Rapid Screen of Concussion (RSC; Comerford, Geffen, May, Medland & Geffen, 2002) and the Digit Symbol Substitution Test, finger tapping speed accounted for 1% of between groups variance and did not improve classification rates of male participants. While the addition of tapping rate did not improve the sensitivity and specificity of the RSC and DSST to mTBI in males, univariate analysis of motor performance in females indicated that dual task performance might be diagnostic. An increase in female sample size is warranted. These results confirm the view that there is a generalized slowing of processing ability following mTBI.
本研究旨在调查轻度创伤性脑损伤（mTBI）对手指敲击和单词重复双重任务表现的急性影响，以确定mTBI中的工作记忆损害。64例（50例男性，14例女性）右利手mTBI患者和26例（18例男性和8例女性）右利手骨科损伤患者在受伤后24小时内接受测试。mTBI患者在10秒内完成的正确敲击次数少于骨科损伤患者，女性mTBI患者重复的单词更少。双重任务减量的大小在各组之间没有差异。当添加到包括快速脑震荡筛查（RSC；Comerford、Geffen、May、Medland和Geffen，2002）和数字符号替换测试的测试组合中时，手指敲击速度占组间方差的1%，并且没有提高男性参与者的分类率。虽然添加敲击速度并没有提高RSC和DSST对男性mTBI的敏感性和特异性，但对女性运动表现的单变量分析表明，双重任务表现可能具有诊断价值。有必要增加女性样本量。这些结果证实了以下观点：mTBI后存在处理能力的普遍减慢。
