Timmer Jorik R, van der Horst Iwan C C, de Luca Giuseppe, Ottervanger Jan Paul, Hoorntje Jan C A, de Boer Menko-Jan, Suryapranata Harry, Dambrink Jan-Henk E, Gosselink Marcel, Zijlstra Felix, van 't Hof Arnoud W J
Department of Cardiology, Isala Klinieken, Locatie Weezenlanden, Zwolle, The Netherlands.
Am J Cardiol. 2005 Jun 1;95(11):1375-7. doi: 10.1016/j.amjcard.2005.01.088.
Patients with diabetes mellitus (DM) have an adverse prognosis after ST-segment elevation myocardial infarction (STEMI). Whether DM was associated with impaired myocardial reperfusion after successful primary percutaneous coronary intervention for STEMI was investigated. Myocardial reperfusion was assessed by ST-segment resolution and myocardial blush grade (MBG). A total of 386 patients were studied, of whom 64 (17%) had DM. These patients more frequently had reduced MBG (20% vs 10%, p = 0.02) and incomplete ST-segment resolution (55% vs 35%, p = 0.02) compared with patients without DM. After multivariate analysis, DM was still associated with impaired ST resolution (odds ratio 2.1, p = 0.03) and reduced MBG (odds ratio 2.2, p = 0.03).
糖尿病（DM）患者在ST段抬高型心肌梗死（STEMI）后预后不良。本研究旨在探讨DM是否与STEMI患者成功进行直接经皮冠状动脉介入治疗后心肌再灌注受损有关。通过ST段回落和心肌 blush 分级（MBG）评估心肌再灌注情况。共研究了386例患者，其中64例（17%）患有DM。与非DM患者相比，这些患者MBG降低（20%对10%，p = 0.02）和ST段不完全回落（55%对35%，p = 0.02）的情况更为常见。多因素分析后，DM仍与ST段回落受损（比值比2.1，p = 0.03）和MBG降低（比值比2.2，p = 0.03）有关。
