Lanz E, Grab B M
Zentrale Abteilung für Anästhesiologie der Krankenhäuser des Landkreises Biberach/Riss.
Anaesthesist. 1992 Apr;41(4):231-4.
Disturbances of micturition following spinal anaesthesia are considered to be rare and harmless side effects of this technique. For this reason, we set up a prospective study to investigate their incidence, characteristics and intensity. Our special interest was directed at the influence of the duration of action of local anaesthetics. METHODS. In a randomized, double-blind study, two groups, each consisting of 73 trauma surgical and orthopaedic patients, received isobaric spinal anaesthesia with either lidocaine 2% or bupivacaine 0.5%. From the 1st to the 3rd postoperative day, the patients were interviewed daily and asked specifically about disturbances of micturition. RESULTS. The two groups were comparable in terms of clinical data, spinal anaesthesia and surgery. Disturbances of micturition occurred only during the first 24 h and were observed in a total of 42%. They were about twice as frequent after bupivacaine (56%) as following lidocaine (27%). After bupivacaine there was a higher rate of difficult micturition or complete inability to micturate in the presence of an urge to urinate, carbachol medication and catheterization of the urinary bladder. Sex and age had no influence on the incidence. A history of disturbances of micturition increased their frequency. DISCUSSION AND CONCLUSIONS. Disturbances of micturition are the most common side effect of spinal anaesthesia during the first 24 h after surgery. Their higher frequency following the longer acting bupivacaine may be evidence of longer lasting blockade of the efferent sacral parasympathetic fibers innervating the detrusor vesicae muscle, leading to inhibition of bladder voiding. The consequences of these disturbances, if not correctly managed, may be distension of the urinary bladder with ensuing infection and loss of tone of the detrusor muscle. Various measures are recommended: choice of the longer acting local anaesthetic only if necessary, careful control of bladder filling, restrictive infusion of fluids, early mobilization, carbachol, catheterization in good time, prophylactic placement of an indwelling catheter in patients with previous disturbances.
脊髓麻醉后排尿障碍被认为是该技术罕见且无害的副作用。因此,我们开展了一项前瞻性研究,以调查其发生率、特征和严重程度。我们特别关注局部麻醉药作用时间的影响。方法:在一项随机双盲研究中,两组各73例创伤外科和骨科患者,分别接受2%利多卡因或0.5%布比卡因等比重脊髓麻醉。术后第1天至第3天,每天对患者进行访谈,特别询问排尿障碍情况。结果:两组在临床资料、脊髓麻醉和手术方面具有可比性。排尿障碍仅发生在最初24小时内,总发生率为42%。布比卡因组(56%)的发生率约为利多卡因组(27%)的两倍。布比卡因组排尿困难或有尿意但完全无法排尿、使用卡巴胆碱药物和膀胱插管的发生率更高。性别和年龄对发生率无影响。既往有排尿障碍病史会增加其发生频率。讨论与结论:排尿障碍是术后最初24小时内脊髓麻醉最常见的副作用。作用时间较长的布比卡因组发生率较高,可能是因为支配膀胱逼尿肌的骶部副交感传出纤维阻滞时间更长,导致膀胱排尿受抑制。如果处理不当,这些障碍的后果可能是膀胱扩张,继而引发感染和逼尿肌失张。建议采取多种措施:仅在必要时选择作用时间较长的局部麻醉药,仔细控制膀胱充盈,限制液体输注,早期活动,使用卡巴胆碱,及时插管,对既往有排尿障碍的患者预防性留置导尿管。