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视频荧光造影联合腾喜龙给药在延髓型重症肌无力诊断中的临床应用

Clinical utility of videofluorography with concomitant Tensilon administration in the diagnosis of bulbar myasthenia gravis.

作者信息

Schwartz Darren C, Waclawik Andrew J, Ringwala Sumit N, Robbins Joanne

机构信息

Department of Medicine, Section of Gastroenterology & Hepatology, University of Wisconsin Medical School, Madison, Wisconsin, USA.

出版信息

Dig Dis Sci. 2005 May;50(5):858-61. doi: 10.1007/s10620-005-2653-2.

Abstract

Myasthenia gravis (MG) classically presents with ocular, bulbar, and predominantly proximal muscle weakness. Isolated bulbar symptoms occur in less than 25% of cases and can mimic stroke (1-3). If left untreated, MG can lead to significant morbidity and mortality, including myasthenic crisis and recurrent aspiration pneumonia. We describe a case of a 68-year-old man who presented with isolated bulbar symptoms. We used a novel approach to diagnosis which included a videofluorographic swallow study with concomitant Tensilon (edrophonium) injection.

摘要

重症肌无力(MG)的典型表现为眼部、延髓部以及主要是近端肌肉无力。孤立的延髓部症状在不到25%的病例中出现,且可能类似中风(1 - 3)。如果不进行治疗,MG可导致严重的发病和死亡,包括重症肌无力危象和反复吸入性肺炎。我们描述了一例68岁男性患者,其表现为孤立的延髓部症状。我们采用了一种新颖的诊断方法,其中包括进行电视透视吞咽研究并同时注射腾喜龙(依酚氯铵)。

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