Schwartz Darren C, Waclawik Andrew J, Ringwala Sumit N, Robbins Joanne
Department of Medicine, Section of Gastroenterology & Hepatology, University of Wisconsin Medical School, Madison, Wisconsin, USA.
Dig Dis Sci. 2005 May;50(5):858-61. doi: 10.1007/s10620-005-2653-2.
Myasthenia gravis (MG) classically presents with ocular, bulbar, and predominantly proximal muscle weakness. Isolated bulbar symptoms occur in less than 25% of cases and can mimic stroke (1-3). If left untreated, MG can lead to significant morbidity and mortality, including myasthenic crisis and recurrent aspiration pneumonia. We describe a case of a 68-year-old man who presented with isolated bulbar symptoms. We used a novel approach to diagnosis which included a videofluorographic swallow study with concomitant Tensilon (edrophonium) injection.
重症肌无力(MG)的典型表现为眼部、延髓部以及主要是近端肌肉无力。孤立的延髓部症状在不到25%的病例中出现,且可能类似中风(1 - 3)。如果不进行治疗,MG可导致严重的发病和死亡,包括重症肌无力危象和反复吸入性肺炎。我们描述了一例68岁男性患者,其表现为孤立的延髓部症状。我们采用了一种新颖的诊断方法,其中包括进行电视透视吞咽研究并同时注射腾喜龙(依酚氯铵)。