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视频荧光造影联合腾喜龙给药在延髓型重症肌无力诊断中的临床应用

Clinical utility of videofluorography with concomitant Tensilon administration in the diagnosis of bulbar myasthenia gravis.

作者信息

Schwartz Darren C, Waclawik Andrew J, Ringwala Sumit N, Robbins Joanne

机构信息

Department of Medicine, Section of Gastroenterology & Hepatology, University of Wisconsin Medical School, Madison, Wisconsin, USA.

出版信息

Dig Dis Sci. 2005 May;50(5):858-61. doi: 10.1007/s10620-005-2653-2.

DOI:10.1007/s10620-005-2653-2
PMID:15906757
Abstract

Myasthenia gravis (MG) classically presents with ocular, bulbar, and predominantly proximal muscle weakness. Isolated bulbar symptoms occur in less than 25% of cases and can mimic stroke (1-3). If left untreated, MG can lead to significant morbidity and mortality, including myasthenic crisis and recurrent aspiration pneumonia. We describe a case of a 68-year-old man who presented with isolated bulbar symptoms. We used a novel approach to diagnosis which included a videofluorographic swallow study with concomitant Tensilon (edrophonium) injection.

摘要

重症肌无力(MG)的典型表现为眼部、延髓部以及主要是近端肌肉无力。孤立的延髓部症状在不到25%的病例中出现,且可能类似中风(1 - 3)。如果不进行治疗,MG可导致严重的发病和死亡,包括重症肌无力危象和反复吸入性肺炎。我们描述了一例68岁男性患者,其表现为孤立的延髓部症状。我们采用了一种新颖的诊断方法,其中包括进行电视透视吞咽研究并同时注射腾喜龙(依酚氯铵)。

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1
Clinical utility of videofluorography with concomitant Tensilon administration in the diagnosis of bulbar myasthenia gravis.视频荧光造影联合腾喜龙给药在延髓型重症肌无力诊断中的临床应用
Dig Dis Sci. 2005 May;50(5):858-61. doi: 10.1007/s10620-005-2653-2.
2
Fiberoptic endoscopic evaluation of swallowing with simultaneous Tensilon application in diagnosis and therapy of myasthenia gravis.在重症肌无力的诊断和治疗中,应用腾喜龙同时进行纤维内镜吞咽评估。
J Neurol. 2008 Feb;255(2):224-30. doi: 10.1007/s00415-008-0664-6. Epub 2008 Jan 28.
3
[Videofluorographic evaluation of dysphagia in a patient with myasthenia gravis].
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Reliability and main findings of the flexible endoscopic evaluation of swallowing-Tensilon test in patients with myasthenia gravis and dysphagia.重症肌无力伴吞咽困难患者行改良胃镜吞咽检查-腾喜龙试验的可靠性及主要发现。
Eur J Neurol. 2018 Oct;25(10):1235-1242. doi: 10.1111/ene.13688. Epub 2018 Jun 22.
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Unusual Presentation of Double-seronegative Myasthenia Gravis with Positive Anti-LRP4 Antibody: Diagnostic Utility of a Videofluoroscopic Swallowing Study.抗LRP4抗体阳性的双阴性重症肌无力的不寻常表现:电视荧光吞咽造影检查的诊断效用
Intern Med. 2025 Jan 15;64(2):307-311. doi: 10.2169/internalmedicine.3348-23. Epub 2024 Jun 20.
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Bulbar Myasthenia Gravis Superimposed in a Medullary Infarction Diagnosed by a Fiberoptic Endoscopic Evaluation of Swallowing With Simultaneous Tensilon Application.

本文引用的文献

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