Vriend Joris W J, Mulder Barbara J M
Department of Cardiology, Academic Medical Centre, Amsterdam, The Netherlands.
Int J Cardiol. 2005 Jun 8;101(3):399-406. doi: 10.1016/j.ijcard.2004.03.056.
Survival of patients with aortic coarctation has dramatically improved after surgical repair became available and the number of patients who were operated and reach adulthood is steadily increasing. However, life expectancy is still not as normal as in unaffected peers. Cardiovascular complications are frequent and require indefinite follow-up. Concern falls chiefly in seven categories: recoarctation, aortic aneurysm formation or aortic dissection, coexisting bicuspid aortic valve, endocarditis, premature coronary atherosclerosis, cerebrovascular accidents and systemic hypertension. In this review, these complications, with particular reference to late hypertension, are discussed and strategies for the clinical management of post-coarctectomy patients are described.
自从有了外科修复手术,主动脉缩窄患者的生存率显著提高,接受手术并成年的患者数量也在稳步增加。然而,预期寿命仍不如未患病的同龄人正常。心血管并发症很常见,需要长期随访。主要关注的问题主要有七类:再缩窄、主动脉瘤形成或主动脉夹层、并存的二叶式主动脉瓣、心内膜炎、过早的冠状动脉粥样硬化、脑血管意外和全身性高血压。在这篇综述中,将讨论这些并发症,特别是晚期高血压,并描述主动脉缩窄切除术后患者的临床管理策略。