平面细胞极性的时间调控：来自果蝇眼睛的见解。
Temporal regulation of planar cell polarity: insights from the Drosophila eye.
作者信息
Schweisguth François
机构信息
Ecole Normale Supérieure, CNRS UMR8542, 46 rue d'Ulm, 75230 Paris Cedex 05, France.
出版信息
Cell. 2005 May 20;121(4):497-499. doi: 10.1016/j.cell.2005.05.006.
PMID:15907460
Abstract
In this issue of Cell, identify a first regulatory link between planar cell polarity (PCP) signaling and apical-basal polarity. The authors propose that a component of the apical Crumbs complex regulates the phosphorylation of the Frizzled (Fz) PCP receptor, thus modulating PCP in the Drosophila eye.
摘要
在本期《细胞》杂志中，发现了平面细胞极性（PCP）信号与顶-基极性之间的首个调控联系。作者提出，顶端Crumbs复合体的一个组分调节卷曲蛋白（Fz）PCP受体的磷酸化，从而在果蝇眼睛中调节PCP。
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