Barbieri Valentina, Lo Russo Giorgio, Francione Stefano, Scarone Silvio, Gambini Orsola
Psychiatric Branch, Department of Medicine, Surgery and Dentistry, University of Milan Medical School and San Paolo Hospital, Milan, Italy.
Epilepsy Behav. 2005 Jun;6(4):617-9. doi: 10.1016/j.yebeh.2005.02.010.
A patient who developed obsessive-compulsive symptoms shortly after the onset of temporal lobe epilepsy exhibited almost complete remission after being rendered seizure-free by surgical intervention. These data support the hypothesis that temporal lobe epilepsy and obsessive-compulsive disorder (OCD) share at least some pathophysiological components. The diagnosis of temporal lobe epilepsy was made by ictal video/EEG recordings, concordant with the presence of a lesion in the posterior region of the temporobasal neocortex. The OCD was diagnosed on the basis of DSM-IV-TR criteria through a clinical interview while the intensity of the OCD symptoms was assessed with the Yape-Brown Obsessive-Compulsive Scale. Surgical intervention consisted of a complete lesionectomy in association with a right temporal lobectomy including both lateral and mesial structures. The patient had follow-up visits after 6 months and 1 year. At both times, the patient remained free of seizures and reported a progressive reduction in OCD symptomatology.
一名在颞叶癫痫发作后不久出现强迫症状的患者，在通过手术干预实现无癫痫发作后，症状几乎完全缓解。这些数据支持了颞叶癫痫和强迫症（OCD）至少共享一些病理生理成分的假说。颞叶癫痫的诊断通过发作期视频/脑电图记录做出，与颞叶基底新皮质后部存在病变相一致。强迫症根据DSM-IV-TR标准通过临床访谈进行诊断，同时使用Yape-布朗强迫量表评估强迫症症状的强度。手术干预包括完整的病灶切除术以及右侧颞叶切除术，包括外侧和内侧结构。该患者在6个月和1年后进行了随访。在这两个时间点，患者均无癫痫发作，且报告强迫症症状逐渐减轻。
