Ardakani M Mazloum, Jalayer M S, Safari J, Sadeghi Z, Zare H R
Department of Chemistry, Faculty of Science, Yazd University, Yazd, Iran.
Anal Biochem. 2005 Jun 15;341(2):259-66. doi: 10.1016/j.ab.2005.03.040.
A new salicylate-selective electrode based on the complex of (2-[(E)-2-(4-nitrophenyl)hydrazono]-1-phenyl-2-(2-quinolyl)-1-ethanone) Cu(II) as the membrane carrier was developed. The electrode exhibited a good Nernstian slope of -59.6+/-1.0 mV/decade and a linear range of 1.0 x 10(-6) to 1.0M for salicylate. The limit of detection was 5.0 x 10(-7) M. The electrode had a fast response time of 10 s and can be used for more than 3 months. The selective coefficients were determined by the fixed interference method and could be used in the pH range of 4.0 to 10.5. The electrode was employed as an indicator electrode for direct determination of salicylate in pharmaceutical and biological samples.
基于（2-[(E)-2-(4-硝基苯基)腙基]-1-苯基-2-(2-喹啉基)-1-乙酮）Cu(II)配合物作为膜载体开发了一种新型水杨酸酯选择性电极。该电极对水杨酸酯表现出良好的能斯特斜率，为-59.6±1.0 mV/十倍浓度变化，线性范围为1.0×10⁻⁶至1.0 M。检测限为5.0×10⁻⁷ M。电极响应时间快，为10 s，可使用3个月以上。通过固定干扰法测定选择性系数，可在pH值4.0至10.5范围内使用。该电极用作指示电极，直接测定药物和生物样品中的水杨酸酯。
