Helps C R, Lait P, Damhuis A, Björnehammar U, Bolta D, Brovida C, Chabanne L, Egberink H, Ferrand G, Fontbonne A, Pennisi M G, Gruffydd-Jones T, Gunn-Moore D, Hartmann K, Lutz H, Malandain E, Möstl K, Stengel C, Harbour D A, Graat E A M
University of Bristol, Bristol BS40 5DU.
Vet Rec. 2005 May 21;156(21):669-73. doi: 10.1136/vr.156.21.669.
A full history of the management practices and the prevalence of upper respiratory tract disease (URTD) at 218 rescue shelters, breeding establishments and private households with five or more cats was recorded. Oropharyngeal and conjunctival swabs and blood samples were taken from 1748 cats. The prevalences of feline herpesvirus (FHV), feline calicivirus (FCV), Chlamydophila felis and Bordetella bronchiseptica were determined by PCR on swab samples. An ELISA was applied to determine the prevalence of antibodies to B. bronchiseptica. The rates of detection by PCR of each pathogen in the cats in catteries with and without ongoing URTD were, respectively, FHV 16 per cent and 8 per cent; FCV 47 per cent and 29 per cent; C. felis 10 per cent and 3 per cent; and B. bronchiseptica 5 per cent and 1.3 per cent; the seroprevalences of B. bronchiseptica were 61 per cent and 41 per cent, respectively. There was evidence that FHV, FCV and B. bronchiseptica played a role in URTD. The risk factors associated with the disease were less than excellent hygiene, contact with dogs with URTD, and larger numbers of cats in the cattery or household.
记录了218个救助庇护所、繁育场所及养猫数量在五只及以上的私人家庭的管理措施及上呼吸道疾病（URTD）的流行情况。从1748只猫身上采集了口咽拭子、结膜拭子和血液样本。通过对拭子样本进行聚合酶链反应（PCR）测定猫疱疹病毒（FHV）、猫杯状病毒（FCV）、猫衣原体和支气管败血博德特氏菌的流行率。应用酶联免疫吸附测定法（ELISA）测定支气管败血博德特氏菌抗体的流行率。在有和没有持续性URTD的养猫场中，通过PCR检测到的每种病原体在猫中的检出率分别为：FHV 16%和8%；FCV 47%和29%；猫衣原体10%和3%；支气管败血博德特氏菌5%和1.3%；支气管败血博德特氏菌的血清流行率分别为61%和41%。有证据表明FHV、FCV和支气管败血博德特氏菌在URTD中起作用。与该疾病相关的风险因素包括卫生条件欠佳、与患有URTD的狗接触以及养猫场或家庭中猫的数量较多。
