Mtvarelidze Z, Kvezereli-Kopadze A, Kvezereli-Kopadze M, Pagava K
I. Pagava Research Institute of Pediatrics, Tbilisi, Georgia; Tbilisi State Medical University, department of Pediatric and Adolescent Medicine.
Georgian Med News. 2005 Apr(121):68-71.
IDA is still the major medico-social problem in pediatric hematology, especially in early childhood. In this correction ferroresistant forms of IDA are interesting. The aim of our investigation was: studying the Efficacy of Tot'hema in the treatment of Iron Deficiency Anemia in Early childhood with concomitant copper deficiency. We observed 42 patients with IDA (age 0,4 - 3 years) in open control investigation. The carried-out investigations revealed that IDA in early childhood is often proceeded by the concomitant copper deficiency and ceruloplasmin, mainly in premature infants and in children with prolonged diarrhea in anamnesis. In such cases it is important to investigate the copper metabolism together with the peripheral blood index and iron metabolism. Tot'hema improves hematologic and biochemical index, completely supplies iron and copper deficiency, prevents of iron resistant form of IDA. Tot'hema has no side effects.
缺铁性贫血(IDA)仍然是儿童血液学中的主要医学社会问题,尤其是在幼儿期。在这种情况下,IDA的铁抵抗形式很有意思。我们研究的目的是:研究托特玛(Tot'hema)治疗幼儿期缺铁性贫血伴铜缺乏的疗效。我们在开放对照研究中观察了42例IDA患者(年龄0.4 - 3岁)。所进行的研究表明,幼儿期的IDA常伴有铜缺乏和铜蓝蛋白缺乏,主要见于早产儿和有长期腹泻病史的儿童。在这种情况下,连同外周血指标和铁代谢一起研究铜代谢很重要。托特玛可改善血液学和生化指标,完全补充铁和铜缺乏,预防IDA的铁抵抗形式。托特玛没有副作用。