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一例由大肠杆菌O111感染所致的溶血性尿毒症综合征合并出血性结肠炎病例

[A case of hemolytic uremic syndrome with hemorrhagic colitis due to Escherichia coli O111 infection].

作者信息

Kim Jong Pyo, Han Dong Soo, Paik Chang Hee, Chung Yong Woo, Kim Jin Bae, Sohn Joo Hyun, Hahm Joon Soo

机构信息

Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea.

出版信息

Korean J Gastroenterol. 2005 May;45(5):365-8.

Abstract

Shiga toxin producing E. coli (STEC) may cause severe hemorrhagic colitis followed by hemolytic uremic syndrome (HUS). In Korea, there had been a few case reports of HUS by STEC, mostly due to O157 serotype. The reports of HUS caused by STEC non-O157 serotype were rare. We report a sporadic case of HUS associated with hemorrhagic colitis. A 51-year-old woman was admitted to our hospital due to intractable abdominal pain and bloody diarrhea. Three days after admission, azotemia and microangiopathic hemolysis developed. E. coli, serotype O111 was identified. Conservative management with plasmapheresis resulted in a complete recovery.

摘要

产志贺毒素大肠杆菌(STEC)可引发严重的出血性结肠炎,继而导致溶血尿毒综合征(HUS)。在韩国,有少数关于STEC所致HUS的病例报告,大多由O157血清型引起。由非O157血清型STEC导致HUS的报告较为罕见。我们报告1例与出血性结肠炎相关的散发性HUS病例。一名51岁女性因顽固性腹痛和血性腹泻入院。入院3天后出现氮质血症和微血管病性溶血。鉴定为O111血清型大肠杆菌。采用血浆置换的保守治疗使其完全康复。

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