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[鸡慢肌和快肌中乙酰胆碱酯酶的分子形式]

[Molecular forms of acetylcholinesterase in the slow muscle and the fast muscle of the chicken].

作者信息

Koenig J, Vigny M

出版信息

C R Seances Soc Biol Fil. 1978;172(6):1069-74.

PMID:159094
Abstract

Five molecular forms of AChE are present in the slow (ALD) and twitch (PLD) muscles of the chick. These forms have 4 S, 7 S, 11 S, 15 S and 20 S sedimentation coefficient in sucrose gradient. The heaviest forms, the 20 S and 15 S of AChE are absent in uninnervated muscles and present in innervated muscles. In innervated muscles, the 20 S and 15 S AChE are present in both nerve-free segments and end-plates zones. The 20 S and 15 S which are not specifically associated with the end-plate zones in the chick could be considered as a biochemical "marker" of neuromuscular interactions.

摘要

鸡的慢肌(ALD)和快肌(PLD)中存在五种乙酰胆碱酯酶分子形式。这些形式在蔗糖梯度中的沉降系数分别为4S、7S、11S、15S和20S。最重的形式,即乙酰胆碱酯酶的20S和15S,在未受神经支配的肌肉中不存在,而存在于受神经支配的肌肉中。在受神经支配的肌肉中,20S和15S乙酰胆碱酯酶存在于无神经节段和终板区。鸡中与终板区无特异性关联的20S和15S可被视为神经肌肉相互作用的生化“标志物”。

相似文献

1
[Molecular forms of acetylcholinesterase in the slow muscle and the fast muscle of the chicken].[鸡慢肌和快肌中乙酰胆碱酯酶的分子形式]
C R Seances Soc Biol Fil. 1978;172(6):1069-74.
2
Acetylcholinesterase in singly and multiply innervated muscles of normal and dystrophic chickens. II. Effects of denervation.
J Exp Zool. 1975 Aug;193(2):191-200. doi: 10.1002/jez.1401930208.
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Influence of innervation on molecular forms of acetylcholinesterase in regenerating fast and slow skeletal muscles.
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[Molecular forms of acetylcholinesterase in frog skeletal muscle: effects of denervation].[青蛙骨骼肌中乙酰胆碱酯酶的分子形式:去神经支配的影响]
C R Seances Soc Biol Fil. 1981;175(3):316-22.
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Neural control of the forms of acetylcholinesterase in slow mammalian muscles.
Nature. 1986;321(6065):72-4. doi: 10.1038/321072a0.
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Satellite cells in slow and fast rat muscles differ in respect to acetylcholinesterase regulation mechanisms they convey to their descendant myofibers during regeneration.在再生过程中,慢肌和快肌中的卫星细胞向其后代肌纤维传递的乙酰胆碱酯酶调节机制有所不同。
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Posthatching changes in levels and molecular forms of acetylcholinesterase in slow and fast muscles of the chicken: effects of denervation and direct electrical stimulation.
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Reciprocal neural regulation of extrajunctional acetylcholinesterase and collagen Q in rat muscles--the role of calcineurin signaling.大鼠肌肉中接头外乙酰胆碱酯酶与胶原蛋白Q的相互神经调节——钙调神经磷酸酶信号传导的作用
Chem Biol Interact. 2008 Sep 25;175(1-3):45-9. doi: 10.1016/j.cbi.2008.05.007. Epub 2008 May 15.

引用本文的文献

1
Appearance of acetylcholinesterase molecular forms in noninnervated cultured primary chick muscle cells.非神经支配的原代培养鸡肌细胞中乙酰胆碱酯酶分子形式的出现
Cell Mol Neurobiol. 1983 Sep;3(3):263-77. doi: 10.1007/BF00710952.