Ojukwu J U, Onwe O E, Modebe O, Imo A O C, Njeze M R
Department of Paediatrics, Ebonyi State University Teaching Hospital, P. M. B. 077, Abakaliki, Ebonyi State, Nigeria.
West Afr J Med. 2005 Jan-Mar;24(1):81-5. doi: 10.4314/wajm.v24i1.28171.
A case of idiopathic central precocious puberty, a rare condition is reported in a 2 1/2 year-old Nigerian boy. He presented with progressive genital growth, a growth spurt, advanced skeletal maturation, and inappropriately high serum concentrations of pituitary and gonadal sex homones for his age. There was no family history of precocious puberty. Physical examination and investigations revealed no identifiable cause for his precocity. Despite the overwhelming problems of malnutrition and infectious diseases in our environment, clinicians must have a high index of suspicion for endocrine disorders.
本文报告了一例特发性中枢性性早熟病例，患者为一名2岁半的尼日利亚男孩，此病较为罕见。他表现为生殖器逐渐发育、生长加速、骨骼成熟提前，且其血清中垂体和性腺性激素浓度与其年龄不符地偏高。其家族中无性早熟病史。体格检查和各项检查均未发现导致他性早熟的明确病因。尽管我们所处环境中存在严重的营养不良和传染病问题，但临床医生仍必须对内分泌紊乱保持高度的怀疑指数。
