Wallace M R, MacKay E O, Gelatt K N, Andrew Stacy E
Department of Molecular Genetics, and Pediatric Genetics, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Vet Ophthalmol. 2005 May-Jun;8(3):203-5. doi: 10.1111/j.1463-5224.2005.00359.x.
To determine the mode of inheritance of cataract formation in the Bichon Frise.
Thirty-six closely related Bichon Frise dogs in a pedigree of 61 dogs were examined using slit-lamp biomicroscopy and indirect ophthalmoscopy over a period of 10 years.
Of the 61 related dogs, 36 were examined repeatedly. Twelve cataractous dogs were diagnosed (three males and nine females). Cataractous dogs resulted from matings between unaffected parents, and when one parent was cataractous and the other parent was unaffected. Age at onset of cataract formation ranged from 18 to 160 months. Available information suggests that the cataracts are inherited as an autosomal recessive trait.
Cataracts appear inherited in the Bichon Frise as an autosomal recessive trait. Additional cataract x cataract matings are necessary to confirm the autosomal recessive heredity.
确定比熊犬白内障形成的遗传模式。
在10年时间里，使用裂隙灯生物显微镜检查和间接检眼镜检查了一个61只犬的家系中的36只亲缘关系密切的比熊犬。
在61只相关犬中，36只接受了反复检查。诊断出12只患有白内障的犬（3只雄性和9只雌性）。白内障犬来自未受影响的父母之间的交配，以及一方患有白内障而另一方未受影响的交配。白内障形成的发病年龄在18至160个月之间。现有信息表明，白内障作为常染色体隐性性状遗传。
比熊犬的白内障似乎作为常染色体隐性性状遗传。需要额外进行白内障×白内障的交配来确认常染色体隐性遗传。
