迷你雪纳瑞先天性白内障和小眼症的遗传

Inheritance of congenital cataracts and microphthalmia in the Miniature Schnauzer.

作者信息

Gelatt K N, Samuelson D A, Bauer J E, Das N D, Wolf E D, Barrie K P, Andresen T L

出版信息

Am J Vet Res. 1983 Jun;44(6):1130-2.

Abstract

Congenital cataracts and microphthalmia in the Miniature Schnauzer were inherited as an autosomal recessive trait. Eighteen matings of affected X affected Miniature Schnauzers resulted in 87 offspring with congenital cataracts and microphthalmia (49 males/38 females). Two matings of congenital cataractous and microphthalmic Miniature Schnauzers (2 females) X a normal Miniature Schnauzer (1 male) yielded 11 clinically normal Miniature Schnauzers (7 males/4 females). Eighteen matings of congenital cataractous and microphthalmic Miniature Schnauzers (6 males) X carrier Miniature Schnauzers (9 females) produced 81 offspring; 39 exhibited congenital cataracts and microphthalmia (20 males/19 females) and 42 had clinically normal eyes (17 males/25 females).

摘要

迷你雪纳瑞的先天性白内障和小眼症以常染色体隐性性状遗传。18对患先天性白内障和小眼症的迷你雪纳瑞进行交配，产生了87只患有先天性白内障和小眼症的后代（49只雄性/38只雌性）。2对患先天性白内障和小眼症的迷你雪纳瑞（2只雌性）与1只正常迷你雪纳瑞（1只雄性）交配，生出了11只临床检查正常的迷你雪纳瑞（7只雄性/4只雌性）。18对患先天性白内障和小眼症的迷你雪纳瑞（6只雄性）与携带致病基因的迷你雪纳瑞（9只雌性）交配，产生了81只后代；其中39只表现出先天性白内障和小眼症（20只雄性/19只雌性），42只眼睛临床检查正常（17只雄性/25只雌性）。