Liaw Yun-Fan, Leung Nancy, Guan Richard, Lau George K K, Merican Ismail, McCaughan Geoff, Gane Edward, Kao Jia-Horng, Omata Masao
Liver Research Unit, Chang Gung Memorial Hospital, Taipei, Taiwan.
Liver Int. 2005 Jun;25(3):472-89. doi: 10.1111/j.1478-3231.2005.01134.x.
BACKGROUND/AIMS: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update.
New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL.
Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested.
The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.
背景/目的:大量关于慢性乙型肝炎治疗的新数据已可获取,因此2003年的共识声明需要修订和更新。
在一次专家会前会议上展示、讨论并辩论了新数据,以起草一份修订稿。修订内容在亚太肝脏研究学会(APASL)全体会议讨论后最终确定。
回顾了概念背景,包括现有和新出现药物的疗效和安全性概况。形成了19条建议,并提出了未解决的问题和进一步研究的领域。
慢性乙型肝炎的当前治疗效果一般但并不令人满意。需要开发新药和新策略以进一步改善治疗结果。