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膀胱全切术后采用去管化乙状结肠新膀胱与去管化W形回肠新膀胱作为膀胱替代物的比较:一项60例患者的研究

Detubularized sigmoid neobladder versus detubularized W-shaped ileal neobladder as a bladder substitute after radical cystectomy for carcinoma of the urinary bladder: a study of 60 patients.

作者信息

Bassiouny Mahmoud, Zaghloul Ashraf S, El Sherbiny Magdy, Saber Nagi, Abdalla Hassan, Shokry Ahmad

机构信息

Department of Surgical Oncology, National Cancer Institue, Cairo University.

出版信息

J Egypt Natl Canc Inst. 2004 Jun;16(2):76-84.

Abstract

OBJECTIVES

To compare the urodynamic parameters, continence rates, and complications between two different continent urinary reservoirs-the sigmoid neobladder (SN) and W-shaped ileal neobladder (IN).

MATERIAL AND METHODS

Sixty patients with bladder cancer underwent radical cystectomy and were divided into two groups. The first group comprised 33 patients who underwent detubularized sigmoid neobladder surgery. The second group included 27 patients who underwent detubuarized W-shaped ileal neobladder surgery.

RESULTS

Early post-operative complications occurred in 42% of patients in the sigmoid neobladder (SN) group and in 33% of patients in the ileal neobladder (IN) group. Most of these complications were minor, mainly due to wound infection or urinary leak, and were managed conservatively. No early post-operative mortality occurred in patients of either group. Day-time continence was achieved in 78.8% and 74% of patients in the SN group and the IN groups, respectively. Night-time continence was achieved in 45.5% of patients in the former group and 59.3% of patients in the latter. The mean neobladder capacity was 472.5cc in patients who underwent detubularized SN surgery and 463.8cc in patients who underwent detubularized IN surgery. The mean post-voiding residual volume was slightly lower in SN group (90.1cc) than in those of IN group (93.7cc). The pelvicalyceal systems were preserved in 94% of patients in the SN group and in 96.3% of patients in the IN group. No significant metabolic disturbances occurred in patients of either group.

CONCLUSIONS

Both methods are good alternatives as a bladder substitute. Surgeon preference, ease of construction and length of mesentery are among the factors that must be considered when choosing between them.

摘要

目的

比较两种不同的可控性尿流改道术——乙状结肠新膀胱(SN)和W形回肠新膀胱(IN)的尿动力学参数、控尿率及并发症。

材料与方法

60例膀胱癌患者接受根治性膀胱切除术,分为两组。第一组33例患者接受去管化乙状结肠新膀胱手术。第二组27例患者接受去管化W形回肠新膀胱手术。

结果

乙状结肠新膀胱(SN)组42%的患者出现早期术后并发症,回肠新膀胱(IN)组为33%。这些并发症大多为轻微并发症,主要是伤口感染或尿漏,采用保守治疗。两组患者均未发生早期术后死亡。SN组和IN组分别有78.8%和74%的患者实现日间控尿。前一组45.5%的患者和后一组59.3%的患者实现夜间控尿。接受去管化SN手术的患者新膀胱平均容量为472.5cc,接受去管化IN手术的患者为463.8cc。SN组的平均排尿后残余尿量(90.1cc)略低于IN组(93.7cc)。SN组94%的患者和IN组96.3%的患者保留了肾盂肾盏系统。两组患者均未发生明显的代谢紊乱。

结论

两种方法都是很好的膀胱替代方案。在两者之间进行选择时,必须考虑外科医生的偏好、构建的难易程度和肠系膜长度等因素。

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