Mäurer M, Linker R, Reinhardt M, Hauff P
Neurologische Klinik der Bayerischen Julius Maximilians-Universität Würzburg.
Radiologe. 2005 Jun;45(6):560-8. doi: 10.1007/s00117-005-1215-0.
Non-invasive molecular imaging technologies provide researchers with the opportunity to study cellular and molecular processes. Among different imaging technologies, ultrasound based molecular imaging methods are also of interest, since the use of ultrasound contrast agents allows specific and sensitive depiction of molecular targets. Recent studies are encouraging and have demonstrated the feasibility of ultrasound based molecular imaging. This review summarizes current experiences and recent preclinical studies with target-specific ultrasound contrast agents.
非侵入性分子成像技术为研究人员提供了研究细胞和分子过程的机会。在不同的成像技术中,基于超声的分子成像方法也备受关注,因为使用超声造影剂能够对分子靶点进行特异性和灵敏的描绘。近期的研究令人鼓舞,并已证明了基于超声的分子成像的可行性。本综述总结了使用靶向特异性超声造影剂的当前经验和近期临床前研究。