Nelson William H
Department of Physics and Astronomy, Georgia State University, Atlanta, Georgia 30303, USA.
Radiat Res. 2005 Jun;163(6):673-80. doi: 10.1667/rr3372.
This work develops a modified description of the dose-response relationships for radical production by ionizing radiation. The main new feature is incorporation of the concept of the target and the possibility that the population of targets can undergo depletion at increased doses. The resulting mathematical relationships are capable of describing the decrease in product yield at increasing doses as is sometime observed. In addition, the description preserves the general properties of the widely used relationships. Finally, the expressions provide the possibility for estimating the average mass of the target.
这项工作对电离辐射产生自由基的剂量-反应关系进行了改进描述。主要的新特点是纳入了靶标的概念以及在剂量增加时靶标群体可能会发生消耗的可能性。由此产生的数学关系能够描述有时所观察到的随着剂量增加产物产率的下降。此外，该描述保留了广泛使用的关系的一般特性。最后，这些表达式为估计靶标的平均质量提供了可能性。
